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Naturally Occurring Change in Walking Scale Scores

Neurodegen Dis Manag; ePub 2018 Sep 18; Motl, et al

Publish date:: September 28, 2018

Walking impairment does change over time in relapsing-remitting multiple sclerosis (RRMS), and this can be described by 3 patterns of change trajectories that differed based on initial status of walking impairment, a recent study found. 269 persons with RRMS completed the 12-item Multiple Sclerosis Walking Scale (MSWS-12) every 6 months over a 30-month period. Data were analyzed using latent growth curve modeling and latent class growth curve modeling. Researchers found:

Latent growth curve modeling demonstrated that a linear trajectory adequately described the group-level pattern of change in MSWS-12 scores over time.
Latent class growth curve modeling supported a 3-class model for describing the heterogeneity of changes in MSWS-12 scores over time.

Citation:

Motl RW, Sandroff BM, McAuley E. Naturally occurring change in Multiple Sclerosis Walking Scale-12 scores over time in multiple sclerosis. [Published online ahead of print September 18, 2018]. Neurodegen Dis Manag. doi:10.2217/nmt-2018-0016.

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