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Fracture With ADHD Medications

Osteoporos Int; ePub 2016 Feb 29; Perry, et al

Publish date:: March 14, 2016

3 times as many patients with no documented attention deficit/hyperactivity disorder (ADHD) medication prescriptions sustain a fracture vs patients with a history of 2 or more prescriptions for an ADHD medication. This from a study of 10,066 patients with ADHD aged ≤ 40 years. Researchers found:

• 10% of patients sustained fractures.

• Multivariable analysis showed that patients without documented medication therapy had a significantly increased hazard of fracture (HR=3.9) vs those with 2 or more prescriptions for an ADHD medication.

• But, the hazard ratio for stimulant vs non-stimulant medication (HR=0.92) was not statistically significant.

Citation: Perry BA, Archer KR, Song Y, et al. Medication therapy for attention deficit/hyperactivity disorder is associated with lower risk of fracture: a retrospective cohort study. [Published online ahead of print February 29, 2016]. Osteoporos Int. doi:10.1007/s00198-016-3547-1.

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