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PF-10a Feasibility in Diverse RA Population

Arthritis Care Res; ePub 2017 Feb 25; Wahl, et al

The 10-item Patient-Reported Outcomes Measurement Information System (PROMIS) physical function form (PF-10a) was feasible to implement in a diverse rheumatoid arthritis (RA) population, a recent study found. Clinical and demographic data were abstracted from electronic health records for all RA patients seen at a university-based rheumatology clinic between February 2013 and February 2015. Researchers evaluated floor and ceiling (edge) effects and construct validity of PF-10a in a subgroup of patients with Health Assessment Questionnaire (HAQ) scores (n= 189). They used linear mixed-effects models to assess responsiveness of PF-10a to longitudinal changes in the Clinical Disease Activity Index (CDAI) for patients in the entire clinical cohort, with both scores recorded on at least 2 encounters (n=326). They found:

  • Half of the patients were nonwhite, and 15% were non-English speakers.
  • Over a 2-year period, PF10a was successfully implemented; 97% of patients and 89% of encounters had at least 1 measurement performed.
  • PF-10a had fewer ceiling (defined as best) effects than the HAQ (8% vs 22%), and convergent validity was high.

Citation:

Wahl E, Gross A, Chernitskiy V, et al. Validity and responsiveness of a 10-Item Patient-Reported Measure of Physical Function in a rheumatoid arthritis clinic population. [Published online ahead of print February 25, 2017]. Arthritis Care Res. doi:10.1002/acr.22956.