Rare Diseases
Photo Challenge
Hyperpigmented Flexural Plaques, Hypohidrosis, and Hypotrichosis
A 61-year-old woman with a history of hypohidrosis and deafness presented with a pruritic rash on the neck and antecubital fossae of several years...
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The challenges of palmoplantar pustulosis and other acral psoriatic disease
Dermatologists are using a variety of treatments for palmoplantar pustulosis, with no clear first-line choices.
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More phase 3 data support use of nemolizumab for prurigo nodularis
"Now I hope you understand why we are so excited," said lead investigator Sonja Ständer, MD.
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Birch bark–derived treatment reduces daily dressings in patients with epidermolysis bullosa
Despite being approved in Europe, Oleogel-S10 has not yet been approved to treat EB in the United States.
News from the FDA/CDC
FDA OKs first ustekinumab biosimilar
The drug has also been granted an interchangeability designation and has been approved for six indications.
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3-D stereophotogrammetry helps detect progression of craniofacial morphea
Existing tools that detect disease progression in patients with CM are limited.
From the Journals
Anti-acid meds lower strength of systemic sclerosis drug
Weakened bioavailability of mycophenolate mofetil could require adjustments in treatment.
Photo Challenge
Disseminated Papules and Nodules on the Skin and Oral Mucosa in an Infant
A 38-week-old infant boy presented at birth with disseminated, nonblanching, purple to dark red papules and nodules on the skin and oral mucosa....
From the Journals
Interstitial lung disease plus pulmonary hypertension equals poor outcomes in systemic sclerosis
Female sex and higher body mass index were associated with lower mortality risk.
Latest News
Mohs found to confer survival benefit in localized Merkel cell carcinoma
Results provide “preliminary data suggesting that treatment of localized, early-stage MCC with MMS may result in the most optimal patient survival...
Make the Diagnosis
A 75-year-old White woman presented with diffuse erythema, scale, and pruritus on her scalp
The patient also had periorbital erythema, as well as erythema on the distal interphalangeal joints.