NORD and Neurology Reviews together have published the third annual Rare Neurological Disease Special Report in print and digital editions to promote awareness and understanding of rare neurological diseases among medical professionals. The publication includes articles on the efficacy of cannabis in treating children with rare and refractory epilepsy, delays in diagnosis and treatment of infantile spasms, telemedicine, new and potential therapies for rare neuromuscular disorders, and the clinical therapeutic potential of gene therapy.