^{Photo courtesy of Richard P. Usatine, MD and the Color Atlas of Family Medicine. 2nd ed.}

After an incubation period of 4 to 21 days, the classic symptoms of malaise, fever, and red “slapped” cheeks appear, signaling that the child is no longer infectious. Four to 14 days after the onset of symptoms, a pruritic lacy rash covers the entire body, preferentially on the extensor surfaces.^1,2