Applied Evidence
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Applied Evidence
Pregnancy and epilepsy—when you’re managing both
When a patient with epilepsy is pregnant or planning for pregnancy, you face the challenge of balancing the benefits and teratogenic risks of her...
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Applied Evidence
When to suspect bipolar disorder
Bipolar disease is often misdiagnosed, sometimes repeatedly. The screening tool and tips you’ll find here will help you identify patients without...
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Applied Evidence
A view from retirement
Five years after retiring from family practice, I still miss my patients.
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Applied Evidence
Hormone therapy for menopausal symptoms: Putting benefits and risks into perspective
Too many patients have needlessly foregone the relief provided by hormone therapy; timing of treatment can make all the difference.
Clinical Inquiries
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Clinical Inquiries
Which patients benefit from lowering LDL to <100 mg/dL?
EVIDENCE-BASED ANSWER: PATIENTS WHO HAVE CORONARY HEART DISEASE (CHD) or are at high risk for CHD should aim for a low-density lipoprotein (LDL)...
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Clinical Inquiries
Do intra-articular steroid injections affect glycemic control in patients with diabetes?
EVIDENCE-BASED ANSWER: YES, BUT THE CLINICAL IMPORTANCE IS MINIMAL. A single intra-articular steroid injection into the knee produces acute...
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Clinical Inquiries
How should we monitor men receiving testosterone replacement therapy?
EVIDENCE-BASED ANSWER: MONITOR HEMATOCRIT AND BONE MINERAL DENSITY (BMD) (strength of recommendation [SOR]: B, meta-analysis of non–patient-...
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Clinical Inquiries
When should you treat tongue-tie in a newborn?
EVIDENCE-BASED ANSWER: CONSIDER TREATMENT WHEN THE INFANT IS HAVING DIFFICULTY BREASTFEEDING. Infants with mild to moderate tongue-tie, or...
Commentary
Photo Rounds
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Photo Rounds
Multiple facial bumps with weight loss
The large and extensive lesions on this young patient’s face led us to an even more troubling finding.
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Photo Rounds
Ulcer on leg
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Photo Rounds
Large leg lesion
Practice Alert
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Practice Alert
ACIP update: 2 new recommendations for meningococcal vaccine
You now need to give previously vaccinated teens a booster dose at age 16 and protect high-risk patients with a 2-dose primary series.
Medical Verdicts
PURLs
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PURLs
Palliative care: Earlier is better
For patients with metastatic cancer, early palliative care—with a referral at diagnosis—has many benefits.