Rare Diseases
Guidelines
New JIA guidelines emphasize earlier DMARD use
Advances in understanding and treating systemic JIA have led practitioners away from steroids and toward using conventional synthetic and biologic...
Latest News
High early recurrence rates with Merkel cell carcinoma
Approximately 95% of all recurrences happened within 3 years of the initial diagnosis in the prospective cohort study.
Latest News
U.S. FDA declines to approve Amryt’s topical gel for rare skin diseases
The decision comes after the FDA had extended its review of the treatment, oleogel-S10, in November by three months to review additional analyses...
Guidelines
New MIS-C guidance addresses diagnostic challenges, cardiac care
New updates in this third version of the American College of Rheumatology’s guidance include a recommendation for dual therapy with IVIg and...
Commentary
Growth hormone therapy for certain children may help them reach their potential
When should parents consider growth hormone therapy? In what cases is it warranted for children? Dr. Jessica Sparks Lilley discusses the need for...
Feature
Cystic fibrosis in retreat, but still unbeaten
Latest News
Lipedema: A potentially devastating, often unrecognized disease
“If patients with lipedema gain weight, the problem becomes even worse,” Dr. C. William Hanke said.
Latest News
Superficial radiotherapy tied to remission, better quality of life in severe Hailey-Hailey disease
To explore the use of superficial radiotherapy, the investigators analyzed data on 13 patients who received the treatment.
News
FDA approves levoketoconazole for Cushing syndrome
The drug, which inhibits cortisol synthesis, is seen as addressing an unmet need.
From the Journals
Case series show no consensus on treatment for palmoplantar pustulosis, generalized pustular psoriasis
“These case series confirm the rarity of both generalized pustular psoriasis and palmoplantar pustulosis ... and the lack of effective treatment...
Latest News
Triple therapy provides robust and durable benefits in cystic fibrosis
From baseline through 24 weeks, the mean Cystic Fibrosis Questionnaire–Revised (CFQ-R) respiratory domain score - the primary endpoint - increased...