Applied Evidence
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Applied Evidence
The work-up for mixed hyperlipidemia: A case study
This case demonstrates that a history, physical exam, and laboratory studies are all needed to determine if the disorder is primary, secondary, or...
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Applied Evidence
When a fetus survives methotrexate exposure
Whether the drug is used for a medical abortion that ultimately fails or for other conditions when pregnancy is unsuspected, your counsel could be...
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Applied Evidence
Menopause management: How you can do better
Let patients know that hot flashes, vaginal dryness, and other common menopausal symptoms can be treated successfully with hormonal and...
Clinical Inquiries
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Clinical Inquiries
How best to diagnose iron-deficiency anemia in patients with inflammatory disease?
EVIDENCE-BASED ANSWER: THE SERUM FERRITIN LEVEL is the most sensitive and specific initial laboratory test for iron-deficiency anemia (IDA) in...
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Clinical Inquiries
Is high-dose oral B12 a safe and effective alternative to a B12 injection?
EVIDENCE-BASED ANSWER: YES. Both high-dose oral B12 and injected B12 raised low vitamin B12 levels and improved hematologic parameters and...
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Clinical Inquiries
What nutritional deficiencies and toxic exposures are associated with nail changes?
EVIDENCE-BASED ANSWER: INFANTS WITH IRON DEFICIENCY have a higher rate of koilonychia—concavity of the outer surface of the nail—(strength of...
Commentary
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Commentary
It takes a village
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Commentary
20 years later, not much has changed
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Commentary
Inhaler use: Tell patients to purse their lips
Original Research
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Original Research
Fatty liver disease in type 2 diabetes: Common and often unmanaged
This study of patients with type 2 diabetes in a large rural clinic showed that abnormal liver function tests do not usually lead to diagnostic...
Photo Rounds
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Photo Rounds
Acral papular rash in a 2-year-old boy
Was this rash linked to the patient’s recent viral infection?
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Photo Rounds
Purple growths on arm
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Photo Rounds
Spots on tongue
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Photo Rounds
Red patches on face
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Photo Rounds
Deformity of foot
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Photo Rounds
Abdominal mass
Practice Alert
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Practice Alert
ACIP immunization update
Males ages 11 to 12 years should routinely receive quadrivalent vaccine against human papillomavirus; patients through age 59 years who have...
PURLs
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PURLs
Counseling is a must with this smoking cessation aid
For many smokers, the benefits of quitting will outweigh the risks associated with varenicline.
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PURLs
BP meds: This simple change improves outcomes
For patients with uncontrolled hypertension, a switch to bedtime dosing is advisable.