Applied Evidence

The skin disorders of pregnancy: A family physician’s guide

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Pathophysiology. Like so many of these conditions, the pathophysiology of PFP is unknown. There is little evidence that the condition is immunologically or hormonally mediated, and there is no evidence of an infectious component.24,29

Differential. PFP must be distinguished from infectious folliculitis, acneiform disorders, HIV-associated eosinophilic folliculitis, and a drug reaction.

Diagnosis. The clinical diagnosis is based on presenting symptoms and third trimester onset. No specific lab or histological analysis can be used to make a definitive diagnosis.

Treatment. As the condition is, by definition, a nonmicrobial folliculitis, the most effective therapy tends to be with mid- to lowpotency topical steroids such as triamcinolone or desonide. Additionally, benzoyl peroxide wash can be effective.

Sequelae. One study reports an increased incidence of low birth weight, but currently no associated morbidity or mortality has been reported.24

FIGURE 5
Pruritic folliculitis of pregnancy

CORRESPONDENCE
Matthew Bremmer, MD, 419 W Redwood Street, Department of Dermatology, Baltimore, MD 21230; Mbrem001@umaryland.edu

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