Asthma
Clinical Inquiries
How often is coughing the presenting complaint in patients with gastroesophageal reflux disease?
EVIDENCE-BASED ANSWER: Frequent coughing is a concern for approximately 35% of those with typical gastroesophageal reflux disease (GERD) symptoms...
Q&A
In children hospitalized for asthma exacerbations, does adding ipratropium bromide to albuterol and corticosteroids improve outcome?
Goggin N, Macarthur C, Parkin PC. Randomized trial of the addition of ipratropium bromide to albuterol and corticosteroid therapy in children...
Q&A
Is a 2-day course of oral dexamethasone more effective than 5 days of oral prednisone in improving symptoms and preventing relapse in children with acute asthma?
Qureshi F, Zaritsky A, Poirier MP. Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma. J Pediatr 2001;...
Q&A
In patients with asthma that is not well controlled with inhaled steroids, does salmeterol (Serevent) or montelukast (Singulair) offer better symptom relief?
Wilson AM, Dempsey OJ, Sims EJ, Lipworth BJ. Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled...
Original Research
Fluticasone Propionate Compared with Zafirlukast in Controlling Persistent Asthma A Randomized Double-Blind, Placebo-Controlled Trial
Q&A
Is budesonide or nedocromil superior in the long-term management of mild to moderate asthma in children?
Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med 2000; 343:...
Q&A
Does exposure of young children to older siblings or to children at day-care facilities protect against the development of asthma later in childhood?
Ball TM, Castro-Rodriguez JA, Griffith KA, Holberg CJ, Martinez FD, Wright AL. Siblings, day-care attendance, and the risk of asthma and wheezing...
Q&A
Do African American asthmatics perceive and describe their asthma symptoms differently than white asthmatics?
Hardie, GE, Janson, SJ, Gold WM, et al. Ethnic descriptors used by African-American and white asthma patients during induced bronchoconstriction....
Q&A
Is there a clinical difference in outcomes when b-agonist therapy is delivered through metered-dose inhaler (MDI) with a spacing device compared with standard nebulizer treatments in acutely wheezing children?
Mandelberg A, Tsehori S, Houri S, et al. Is nebulized aerosol treatment necessary in the pediatric emergency department? Comparison with a metal...
Q&A
In children with asthma, do inhaled steroids reduce linear growth (height)?
Sharek PJ, Bergman DA. Beclomethasone for asthma in children: effects on linear growth. The Cochrane library Oxford, England: Update Software;...
Q&A
In patients with stable persistent asthma, can lower doses of inhaled corticosteroid medication control symptoms and maintain optimal pulmonary function as well as high doses?
Foresi A, Morelli MC, Catena E. Low-dose budesonide with the addition of an increased dose during exacerbations is effective in long-term asthma...