Q&A
Q&A
Are glucosamine and chondroitin effective in treating osteoarthritis?
McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and...
Q&A
What is the long-term efficacy and tolerability of orlistat, a gastrointestinal lipase inhibitor, for the treatment of obesity in primary care?
Hauptman J, Klebanoff MA, Hauth JC, et al. Orlistat in the long-term treatment of obesity in primary care settings. Arch Fam Med 2000; 9:160-7.
Q&A
Is a 7-day course of ciprofloxacin effective in the treatment of uncomplicated pyelonephritis in women?
Talan DA, Stamm WE, Hooton TM, et al. Comparison of ciprofloxacin (7 days) and trimethoprim-sulfamethoxazole (14 days) for acute uncomplicated...
Q&A
Is a 3-day hospitalization cost-effective for patients after uncomplicated acute myocardial infarction (AMI)?
Newby, LK, Eisenstein, EL, Califf, RM, et al. Cost effectiveness of early discharge after uncomplicated acute myocardial infarction. N Engl J Med...
Q&A
How frequently should patients with type 2 diabetes mellitus be screened for retinopathy?
Vijan S, Hofer TP, Hayward RA. Cost-utility analysis of screening intervals for diabetic retinopathy in patients with type 2 diabetes mellitus....
Q&A
How effective are antidepressant medications in the treatment of irritable bowel syndrome and nonulcer dyspepsia?
Jackson JL, O’Malley PG, Tomkins G, Balden E, Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant...
Q&A
Does losartan decrease all-cause mortality more than placebo or first-generation ACE inhibitors for patients with moderate to severe heart failure?
Sharma D, Buyse M, Pitt B, et al. Meta-analysis of observed mortality data from all-controlled, double-blind, multiple dose studies of losartan in...
Q&A
What is the long-term prognosis of patients with Lyme disease?
Seltzer EG, Gerber MA, Cartter ML, Freudigman K, Shapiro ED. Long-term outcomes of persons with Lyme disease. JAMA 2000; 283:609-16.
Q&A
Is amoxicillin more effective than placebo in treating acute otitis media in children younger than 2 years?
Damoiseaux RA, van Balen FA, Hoes AW, Verhiej TJ, de Melker RA. Primary care based randomised, double blind trial of amoxicillin versus placebo...
Q&A
Can a program of manual physical therapy and supervised exercise improve the symptoms of osteoarthritis of the knee?
Deyle GD, Henderson NE, Matekel RL, Ryder MG, Garber MB, Allison SC. Effectiveness of manual physical therapy and exercise in osteoarthritis of...
Q&A
Is spiral (helical) computed tomography useful for diagnosing pulmonary embolism?
Mullins MD, Becker DM, Hagspiel KD, Philbrick JT. The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism. Arch...