Rheumatology
Clinical Inquiries
What are effective strategies for reducing the risk of steroid-induced osteoporosis?
EVIDENCE-BASED ANSWER: Calcium, in combination with vitamin D, prevents bone loss and is recommended in all patients. (Grade of recommendation: A...
Applied Evidence
Prevention and Treatment of Osteoporosis in Postmenopausal Women
The goals of therapy for osteoporosis are fracture prevention and pain relief; prior fracture is associated with a fivefold risk of future...
Q&A
Are NSAIDs more effective than acetaminophen in patients with osteoarthritis?
Pincus TG, Koch GG, Sokka T, et al. A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in...
Q&A
Does glucosamine sulfate affect progression of symptoms and joint structure changes in osteoarthritis?
Reginster JY, Leroisy R, Rovati LC, et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomized, placebo-...
Commentary
Old Stone Face
Q&A
Are glucosamine and chondroitin effective in treating osteoarthritis?
McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and...
Q&A
Can a program of manual physical therapy and supervised exercise improve the symptoms of osteoarthritis of the knee?
Deyle GD, Henderson NE, Matekel RL, Ryder MG, Garber MB, Allison SC. Effectiveness of manual physical therapy and exercise in osteoarthritis of...
Q&A
Celecoxib for Rheumatoid Arthritis
Simon LS, Weaver AL, Graham DY, et al. Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis. JAMA 1999; 282:...