Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Must Reads by Date
Must reads for theWeek ending February 17, 2019
Uninterrupted ibrutinib with CAR T may boost outcomes in CLL , Gauthier J et al. ASH 2018, Abstract 299
Follicular lymphoma: MRD response correlates with outcomes , Pott C et al. ASH 2018, Abstract 396.
NEO-PV-01 vaccine shows good tolerability and safety , Hu-Lieskovan S et al. SITC 2018, Abstract 07.
Obesity-related cancers such as kidney cancer rising among young adults, Sung H et al. Lancet Public Health. 2019 Feb 4.
Therapeutic drug monitoring for tamoxifen not justified, Sanchez-Spitman A et al. J Clin Oncol. 2019 Jan 24. doi: 10.1200/JCO.18.00307.
Must reads for theWeek ending February 10, 2019
Physician mothers with extra caregiving at home at higher risk, Yank V et al. JAMA Internal Medicine. 2018 Jan 28. doi: 10.1001/jamainternmed.2018.6411.
Many believe tumor profiling will benefit present treatment, Marron et al. JCO Precis Oncol. 2019 Jan 22. doi: 10.1200/PO.18.00176.
No difference in financial distress with counseling intervention , Kircher SM et al. J Oncol Pract. 2019 Jan 9. doi: 10.1200/JOP.18.00270.
Uninsured rate could rise with proposed premium calculator, Federal Register (84 FR 227)
Over half of Americans support Medicare for All, Kaiser Family Foundation Health Tracking Poll – January 2019
Must reads for theWeek ending February 3, 2019
Tisagenlecleucel responses persist at 18 months in r/r B-cell ALL, Grupp SA et al. ASH 2018, Abstract 895
IDH-mutated AML: First-line IDH inhibitors, chemo may up remission, Stein EM et al. ASH 2018, Abstract 560
With a positive sentinel node, RT better than surgery, Rutgers EJT et al. SABCS 2018, Abstract GS4-01
Genomic characteristics of neuroblastomas linked with outcomes, Ackermann S et al. Science. 2018 Dec 7. doi: 10.1126/science.aat6768
Must reads for theWeek ending January 27, 2019
Crowdsourcing happening at multiple steps in cancer research, Interviews with several leaders in the field
Have clear message to get study published, Annual meeting of the American Society of Hematology
ASCO voices concern over mandatory demonstration program, Centers for Medicare & Medicaid Services
Medical marketing spending increased exponentially, Schwartz LM et al. JAMA. 2019 Jan 8. doi: 10.1001/jama.2018.19320
Price inflation driven by old and new drugs, Hernandez I et al. Health Aff (Millwood). 2019 Jan. doi: 10.1377/hlthaff.2018.05147
Must reads for theWeek ending January 20, 2019
Intensity modulated radiation therapy may be preferable in children with extremity nonrhabdomyosarcoma soft-tissue sarcomas, Source: Rao A et al. Intl J Rad Oncology*Biology*Physics; Jan. 2019, 38-44. https://doi.org/10.1016/j.ijrobp.2018.09.005
TAO: Nonwhite ethnicity, limb infection predict poor prognosis, Le Joncour A et al. Arthritis Rheumatol. 2018;70(Suppl 10): Abstract 1885
Outcomes better in TNBC with adjuvant chemotherapy within 30 days of surgery, Morante Z et al., SABCS 2018 Abstract GS2-05
Ten years of anastrozole boosts disease-free survival, Ohtani S et al. SABCS 2018, Abstract GS3-04
Thrombolysis for acute ischemic stroke safe in GI malignancy, Inohara T et al. Circulation. 2018 Nov 6;138[suppl 1], Abstract A12291