Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending April 5, 2015

AML Care: Good News from SEER database, Change in early death, median survivals

ACS Guidelines: Caring For Prostate Cancer Survivors , Recommendations for treating after-effects of cancer

Predicting Adenomas Prior to Colonoscopy, New model developed for estimating colon cancer risk

Is There a Link Between Breast and Prostate Cancers?, Breast cancer risk exacerbated with family history of both

More must reads

Must reads for theWeek ending March 29, 2015

Observation or Radiotherapy After Breast Conserving Surgery, Which has a lower local failure rate?

A More Accurate Predictor of Breast Cancer, New assessment tool for women with benign breast disease

Improved Prognostic Performance Model for MRCC , IMDC compared with MSKCC model for renal cell carcinoma

Unituxin Approved for High-Risk Neuroblastoma, GD2-binder is first approved for high-risk condition

More must reads

Must reads for theWeek ending March 22, 2015

CDC: Cancer Survival Rates On The Rise, Report highlights incidence and mortality rates by type of cancer

Is Androgen-Deprivation Therapy Monotherapy Enough? , Three-cohort study compares ADT with and without radiotherapy

Increase in Adjuvant Chemotherapy Use in Stage I Breast Cancer, A closer look at treatment rates from 2000 to 2009

Postoperative Radio Therapy Improves Survival in NSCLC, A review of patients from the National Cancer Data Base

FDA Approves First Biosimilar Product Filgrastim-sndz, Injection available in two pre-filled doses

More must reads

Must reads for theWeek ending March 15, 2015

2 Steps to Ensure Melanomas Aren’t Missed, How effective is the dermoscopy algorithm?

Is Colon Resection or CME Surgery More Successful?, Disease-free survival rates in patients with colon adenocarcinoma

Preventing Colorectal Cancer Deaths, More screening recommended

Depigmentation in Melanoma Following Immunotherapy, Vitiligo-like reaction in patients linked to survival

Opdivo Granted Accelerated FDA Approval, PD-1 blocking antibody to treat melanoma, NSCL cancer

More must reads

Must reads for theWeek ending March 8, 2015

FDA Approves Palbociclib for Postmenopausal Breast Cancer, Indicated for ER-positive, HER2-negative patients

FDA Approves New Treatment for Thyroid Cancer, Lenvatinib treats iodine-refractory differentiated disease

FDA Approves Panobinostat for Multiple Myeloma, Accelerated approval due to progression-free survival

Could Allergies Protect Against non-Hodgkin Lymphoma?, Results from the Agricultural Health Study

More must reads

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