Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Eculizumab reduces relapse-related hospitalizations in patients with NMOSD
Key clinical point: Eculizumab reduces relapse-related hospitalizations and associated treatment in patients with NMOSD.
Major finding: The annualized relapse-related hospitalization rate was lower in the eculizumab group (0.04) than in the placebo group (0.31).
Study details: A randomized, double-blind, placebo-controlled study of 143 patients with NMOSD.
Disclosures: Alexion Pharmaceuticals, which markets eculizumab, sponsored the study. Dr. Wingerchuk received grants from Alexion during the study.
Kim H et al. ACTRIMS 2020.
Citation: