Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Incomplete MS relapse recovery predicted greater long-term disability
Key clinical point: Recovery from early MS relapses is an important predictor of future disability.
Major finding: Patients’ recovery index was significantly associated with 10-year Expanded Disability Status Scale scores (P less than .001).
Study details: A review of data from 403 MS attacks in 308 patients enrolled in the CLIMB study.
Disclosures: The CLIMB study received funding from Mallinckrodt and the National MS Society Nancy Davis Center Without Walls. Dr. Sotiropoulos has received research support from Mallinckrodt. Dr. Chitnis has served on advisory boards for Biogen, Novartis, and Sanofi-Genzyme, and she has received research support from the Department of Defense, National MS Society, Guthy-Jackson Charitable Foundation, Novartis, Octave, Serono, and Verily. Dr. Zeydan had no disclosures to report.
Sotiropoulos MG et al. ACTRIMS Forum 2020. Abstract LB 317.