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Myocardial Infarction Associated with Arthritis

Ann Rheum Dis; ePub 2017 Feb 20; Schieir, et al

Myocardial infarction (MI) risk was consistently increased in multiple types of arthritis in population-based studies, and was partially explained by a higher prevalence of traditional risk factors in all types of arthritis, according to a recent study. A medical literature search was performed for population-based cohort or case-control studies published between January 1980 and January 2015, with a measure of effect and variance for associations between incident MI and 5 major types of arthritis: rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), gout or osteoarthritis (OA), adjusted for at least age and sex. Researchers found:

  • A total of 4,285 articles were identified; 27 met review criteria and 25 met criteria for meta-analyses.
  • In studies adjusting for age and sex, MI risk was significantly increased in RA, gout, PsA, and OA and tended towards increased risk in AS.
  • Traditional risk factors were more prevalent in all types of arthritis.

Citation:

Schieir O, Tosevski C, Glazier RH, Hogg-Johnson S, Badley EM. Incident myocardial infarction associated with major types of arthritis in the general population: A systematic review and meta-analysis. [Published online ahead of print February 20, 2017]. Ann Rheum Dis. doi:10.1136/annrheumdis-2016-210275.