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MRI Lesion Patterns in Tibiofemoral and Patellofemoral Joints

Do patterns predict osteoarthritis risk?

Publish date:: October 5, 2015

Different patterns of co-existing MRI lesions were identified in knees free of radiographic osteoarthritis (OA) that have different implications for risk of knee OA, according to a study of 885 knees without radiographic OA in both tibiofemoral and patellofemoral joints. Researchers found:

• 4 latent subgroups were identified in the tibiofemoral joint: minimal lesions, mild lesions, moderate lesions (but limited meniscal lesions), and severe lesions.

• Odd ratios of incident disease in the tibiofemoral joint for the subgroups were 1.0, 5.6, 1.8, and 5.0, respectively.

• A similar set of 4 subgroups was identified in the patellofemoral joint, except that the fourth subgroup had limited meniscal lesions.

• Odds ratios of incident disease in the patellofemoral joing were 1.0, 3.8, 5.1, and 13.7, respectively.

Citation: Niu J, Felson DT, Neogi T, et al. Patterns of co-existing MRI lesions and incident knee osteoarthritis: The MOST Study. [Published online ahead of print September 28, 2015]. Arthritis Rheumatol. doi: 10.1002/art.39436.

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