Clinical Review

Kidney Failure in the 21st Century

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CONCLUSION

The decision to begin renal replacement therapy—whether a form of dialysis, or another management option—depends not on SCr or eGFR alone. Rather, a number of uremic manifestations, comorbidities, lifestyle factors, and other variables must be carefully weighed before the patient, the family, and the clinicians involved can decide on the management plan most likely to enhance the patient’s quality of life and extend survival.

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